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Unraveling the Link Between Stress and Cancer Spread

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The Impact of Chronic Stress While stress is an unavoidable part of life, chronic stress can have detrimental effects on health, increasing the  risk of heart disease , and strokes, and possibly even aiding in the spread of cancer. Understanding the mechanisms underlying this relationship has been a challenge in cancer care, but researchers from Cold Spring Harbor Laboratory (CSHL) may have made a breakthrough in unraveling this complex connection. Discovering the Role of Neutrophils Former postdoc Xue-Yan He and Adjunct Professor Mikala Egeblad, along with CSHL Professor Linda Van Aelst, conducted a study revealing how stress impacts cancer spread. Their research demonstrated that stress triggers certain white blood cells called neutrophils to form sticky web-like structures known as  neutrophil extracellular traps  (NETs). These NETs create an environment conducive to metastasis, facilitating the spread of cancer cells throughout the body. Implications for Treatment an...