Early Detection of Alzheimer’s possible through eye tests, reveals a study
A groundbreaking study has revealed that early signs of Alzheimer’s disease could be identified in a person’s eyes. Published in the journal Acta Neuropathological in February, the study conducted over 14 years examined the pathological features of Alzheimer’s in the retinas of 86 volunteers experiencing cognitive decline. How does it work? Researchers discovered that changes in the retina were associated with changes in the entorhinal and temporal cortices, which are responsible for memory, navigation, and perception of time in the brain. The study also revealed an 80% decline in microglial cells in those with cognitive issues. These cells are responsible for repairing and maintaining other cells, including clearing beta-amyloid from the brain and retina. Lead author of the study, Maya Koronyo-Hamaoui, said to Cedar-Sinai: “Our study is the first to provide in-depth analyses of the protein profiles and the molecular, cellular, and structural effects of Alzheimer’s disease in th...