Protein Misfolding in Alzheimer’s Disease: A Deep Dive into its Role and Implications
Source: Image by Motortion from Getty Images Alzheimer’s disease (AD) is a progressive neurodegenerative brain disorder that destroys memory and other cognitive functions, which results in the cause of dementia eventually. A growing body of evidence emphasizes protein misfolding as a critical biological phenomenon associated with Alzheimer’s disease. In this article, we will uncover the relationship between protein misfolding in Alzheimer’s disease which is key to unraveling the original cause of this condition and developing the proper course of treatment. What is Protein Misfolding? Proteins are the essential workhorses of cellular processes. They perform critical functions ranging from enzymatic activity to structural support. For proteins to function correctly, they must fold into precise three-dimensional shapes. Protein misfolding refers to the process by which proteins fail to attain or maintain their intended structure. When proteins misfold, they lose functio...