Melatonin Use Tied to Higher Risk of Heart Failure, Study Finds
Source: Viktoriya SkorikovaGetty Images Key Points: Long-term melatonin use is linked to a 90% higher risk of heart failure and death. The study was observational, so it doesn’t prove cause and effect. Experts advise caution and medical consultation before long-term use. Long-term use of melatonin supplements may be associated with a higher Melatonin Heart Failure Risk, according to new research to be presented at the American Heart Association’s Scientific Sessions 2025, to be held Nov. 7–10. In a review of medical records, researchers found that adults with chronic insomnia who took melatonin for at least one year had a 90% higher chance of developing heart failure within the next five years compared with those who did not take the supplement. Melatonin users were also more than three times as likely to be hospitalized for heart failure and twice as likely to die from any cause. “Melatonin supplements are widely thought of as a safe and ‘natural’ option to support better sleep,...